Different To vs. Different From vs. Different Than

• ‘How is the patient doctor?’ ‘No different.’
• His ideas are little different from those of his friends.

Quite different means ‘completely different’.

• I thought you would be like your sister, but you are quite different.

Different can also be modified by very.

• She is very different from her sister.

Prepositions after different

From is generally used after different. To is also common in British English.

• American football is very different from/to soccer.

After different, Americans use from or than.

• American football is very different from/than soccer.