We use how to ask about things that change ’ for example, people’s health and moods. We use what — like? to ask about things that do not change – for example, people’s looks and character.
‘How is she?’ ‘She is very well.’
What is she like? She is a bit shy. (NOT How is she?)
What does she look like? She is short, dark and pretty.
We often use how to ask about people’s reactions to their experiences.
‘How was the film?’ ‘Not bad.’
‘How is your new job?’ ‘Quite interesting.’
What — like? is also possible in cases like these.